Lessons inde novopeptide sequencing by tandem mass spectrometry
نویسندگان
چکیده
منابع مشابه
Protein sequencing by tandem mass spectrometry.
Methodology for determining amino acid sequences of proteins by tandem mass spectrometry is described. The approach involves enzymatic and/or chemical degradation of the protein to a collection of peptides which are then fractionated by high-performance liquid chromatography. Each fraction, containing as many as 10-15 peptides, is then analyzed directly, without further purification, by a combi...
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ژورنال
عنوان ژورنال: Mass Spectrometry Reviews
سال: 2013
ISSN: 0277-7037
DOI: 10.1002/mas.21406